A CHRONIC, COMPLEX, AND INFLAMMATORY SKIN DISORDER

For centuries, psoriasis was regarded as a purely epidermal disorder. However, a major paradigm shift occurred in the 1970’s, and today psoriasis is considered an autoimmune disorder where the immune system mistakenly attacks healthy skin cells.

When T-cells from the immune system attack skin cells, the deepest layer of skin begins producing new skin cells more quickly than usual.

Due to this imbalance in the skin’s normal components, the surface of the skin begins shedding, scaling, and flaking.

 

 

Genetic predisposition is a major determining factor in who gets psoriasis. 90% of patients report a positive family history.

PSORIASIS TYPES AND TRIGGERS

There are many forms of psoriasis. These range in severity from a few scattered patches to the covering of almost the entire surface of the body’s skin.

  • Chronic Plaque Psoriasis is the most common type and affects 85-90% of all psoriasis sufferers.
  • Guttate Psoriasis is more commonly seen in children and adolescents and often follows an upper respiratory tract infection.
  • Pustular Psoriasis is a rare form that manifests as white or yellow pus-filled blisters.
  • Inverse of Flexural Psoriasis is characterised by sharply demarcated, smooth, inflamed lesions without significant scaling on certain parts of the body.
  • Scalp Psoriasis affects approximately half of all sufferers. The individual lesions are discrete and often advance to the face.

 

CONVENTIONAL MANAGEMENT
AND QUALITY-OF-LIFE

Timely and ongoing treatment of psoriasis is imperative.

Maintaining quality-of-life and slowing down, or even halting, the progression of psoriasis’ debilitating and sometimes life-threatening complications is dependent upon treating symptoms.

Topical therapy is the primary treatment for most psoriasis patients, but moderate to severe cases may require phototherapy and/or systemic treatment. Conventional psoriasis remedies often have significant side effects, however, which is problematic since most psoriatic patients have a localised condition that doesn’t warrant exposure to high-risk treatments.

Zymbilan® was created to solve this problem by offering both topical and systemic options that are safe to use on a long-term basis and free from side effects.

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